Heart Disease Archive

In a 2025 analysis involving about 200 million people, those who used cannabis had a 29% higher risk for sudden heart attacks or angina and twice the risk of premature death from cardiovascular disease, compared with people who didn’t use cannabis.

There are no medications to treat aortic stenosis (narrowing of the aortic valve), but several possibilities are currently being studied, including a class of drugs to treat diabetes and others that lower high lipoprotein(a) blood levels.

A heart disease diagnosis may trigger a bout of depression. But having depression can also leave people more vulnerable to heart disease. Some of the overlap stems from shared lifestyle factors, such as inactivity and an unhealthy diet. In addition to addressing those issues, other safe and effective ways to ease depression include working with a therapist, using a light box, and taking medications.

If a blood clot lodges in an artery or vein, it can choke off blood flow to the heart, brain, or lung. Often called blood thinners, anti-clotting drugs play a big role in treating heart disease. But they can cause minor (and sometimes serious) bleeding, ranging from nosebleeds to bleeding inside the brain. New solutions to balance clot prevention and excess bleeding are in the works, including low-dose drug combinations and new medications.

Menopausal hot flashes and night sweats, called vasomotor symptoms, are linked in research to higher odds of dementia and cardiovascular disease. But studies don’t necessarily account for other health and lifestyle factors that influence brain and heart health. Women who are physically active and have a lower body mass index are less likely to become cognitively impaired. Disrupted sleep, which is common for women with vasomotor symptoms, may also contribute to cardiovascular and cognitive problems.

A 2025 study suggests that squeezing a week’s worth of exercise (150 minutes) into just one or two days — a “weekend warrior” pattern — is linked to the same heart benefits as daily exercise.

Direct-to-consumer genetic tests can screen for rare heart conditions that arise from variants in a single gene (such as cardiomyopathies) as well as common conditions influenced by many thousands of gene variants (such as coronary artery disease). But because the results are not definitive, they can be challenging to interpret.

A 2025 study found that morning coffee drinkers faced lower odds of dying from cardiovascular disease—or any cause—over a 10-year period compared with people who drank coffee all day or people who didn’t drink coffee at all.

People with very high calcium scores (over 1,000) have a risk of heart attack or stroke similar to those who have already had a heart attack. They should take cholesterol-lowering drugs to bring down LDL levels and possibly undergo additional testing.