Mental Health Archive

At 70 years and counting, the Framingham Heart Study continues to help doctors better understand stroke, dementia, and heart disease.

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In 1948, more than 5,200 people living in a town just west of Boston volunteered for what has evolved into the longest running and best-known study of the causes of heart disease. But the multigenerational Framingham Heart Study has also revealed important clues about brain disorders — most notably stroke but also cognitive decline and dementia (see "Framingham's brain health findings").

In the early 1960s, Framingham researchers coined the term "risk factor," which refers to a characteristic or exposure that raises a person's odds of developing a disease. Over the following decades, they uncovered many such factors for heart disease, including cigarette smoking, obesity, lack of physical activity, and high blood pressure. These habits and conditions also turned out to predispose people to stroke and dementia, thereby establishing that what harms the heart is also bad for the brain.

People often become more sensitive to noise as they age, which can affect their mental and physical health.

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Are you more sensitive to noises than you used to be? Do certain sounds now feel too loud and jarring? Don't worry; it's actually quite normal.

Age-related hearing loss is common among older adults and affects about two-thirds of men in their 70s and 85% of men ages 80 and older. Although it's not clear why, this can also make people hypersensitive to sounds that they used to tolerate easily, which in turn can affect their well-being.

Research we're watching

In December 2018, the FDA issued a warning about certain antibiotics known as fluoroquinolones, a drug class that includes ciprofloxacin (Cipro) and levofloxacin (Levaquin). The drugs are associated with rare ruptures or tears in the body's main artery, the aorta, which can cause serious, sometimes fatal bleeding. Cases were reported in people taking these antibiotics orally or by injection.

Because of this risk, the FDA is advising doctors to try to avoid prescribing these antibiotics to people who are at higher risk for problems with the aorta, unless there are no other antibiotics available to treat the infection. This includes people who have high blood pressure, certain genetic disorders (such as Marfan syndrome and Ehlers-Danlos syndrome), or a history of arterial blockages or aneurysms.

The life of a teenager can be filled with drama, real or imagined. But while parents may think their teen overreacts too much, parents themselves might under-react to indications that a teen could be contemplating suicide.

Stress and depression may lead to new health issues or intensify the symptoms of existing conditions.

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We tend to think of grieving as an emotional experience, and it is — fraught with intense sadness, profound loss, and psychological pain. But grief has a physical side that sets us up for a number of health risks. "Most of these side effects are the result of emotional distress responses," explains Dr. Maureen Malin, a geriatric psychiatrist with Harvard-affiliated McLean Hospital. Whether you're grieving the loss of a loved one, a job, a home, or a beloved pet, it's important to understand how the process puts your health in jeopardy.

Stress and grief

Grieving takes a toll on the body in the form of stress. "That affects the whole body and all organ systems, and especially the immune system," Dr. Malin says. Evidence suggests that immune cell function falls and inflammatory responses rise in people who are grieving. That may be why people often get sick more often and use more health care resources during this period.

The emotional weight of grief affects the body in the form of stress, which can make existing conditions worse or cause new ones, and can also lead to depression. Maintaining health may seem difficult while grieving, but doing so can help rebuild mental strength.

News briefs

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Omega-3 fatty acid supplements may help ease anxiety symptoms in people diagnosed with a range of physical and mental health problems, according to a review published in the Sept. 14, 2018, JAMA Network Open. The report pooled findings from 19 different studies and included 1,200 people. Most of the studies compared omega-3 supplements to a placebo. Taken together, the studies included people with a range of health problems, including heart attacks, attention deficit disorder, substance abuse, depression, and Parkinson's disease, as well as some groups without any specific clinical diagnosis. Researchers found that people who took high doses of omega-3s (up to 2,000 mg a day) seemed to have the most reduction in anxiety symptoms. Omega-3 fatty acids, which are usually derived from fish oil, have a number of biological effects in the body. Brain membranes contain a high proportion of these fats, and human studies suggest that a lack of omega-3s in the brain may induce various behavioral and psychiatric disorders. For now, it's too soon to recommend high-dose omega-3 supplements for treating anxiety. Larger trials testing the supplements (both alone and combined with standard treatments) are needed, the study authors say.

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In the journals

People with atrial fibrillation, or afib, a type of irregular heartbeat that is linked with stroke, also may have a greater risk of dementia than those without the condition, according to a study published online Oct. 10, 2018, by Neurology.

Researchers recorded medical data from 2,685 people, average age 73. None of them had dementia and 243 had afib. After nine years, another 279 people developed afib. The researchers found that people with afib showed a faster rate of decline in thinking and memory skills than those without the condition, and were 40% more likely to develop dementia.