Nutrition Archive

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Food and mood: Is there a connection?

Here's what the research says about diet and depression.


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If you've ever found yourself in front of the TV after a bad day, mindlessly digging ice cream out of the container with a spoon, you know that mood and food are sometimes linked. But while stress eating is a verified phenomenon, the relationship between food and actual mood disorders, such as depression, is less clear. Or, to put it another way: can the things you eat influence your risk for depression — and can dietary changes potentially improve your mental health?

"The research regarding dietary factors and depression is still inconclusive," says Patricia Chocano-Bedoya, a visiting scientist in the Department of Nutrition at the Harvard T.H. Chan School of Public Health. But there have been hints that food may play a role in depression.

Can diet heal chronic pain?

The foods you eat (and don't) can determine how well your body fights painful inflammation.


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It's been said that you are what you eat, and that's definitely true when it comes to chronic pain.

"A lot of chronic pain is the result of chronic inflammation, and the evidence is quite strong that your diet can contribute to increased systemic inflammation," says Dr. Fred Tabung, a visiting researcher with the Department of Nutrition at Harvard's T.H. Chan School of Public Health. "But your diet is also one of the best ways to reduce it."

Precious metals and other important minerals for health

Make sure your diet meets the recommended mineral targets.


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Gold, silver, and platinum get all the attention as the world's most precious metals. But they're more precious for the global economy than for human health. Instead, other metals and minerals (metals are one type of mineral) are more important for our health (see "What essential metals do for us"). Indeed, some of them are so important that we can't live without them. "Each one plays a role in hundreds of body functions. It may take just a very small quantity of a particular mineral, but having too much or too little can upset a delicate balance in the body," says Dr. Bruce Bistrian, chief of clinical nutrition at Beth Israel Deaconess Medical Center.

What essential metals do for us

Many metals are used to make strong and durable everyday objects, like copper pipes or iron skillets. But they don't form such strong and durable objects in our bodies. Instead, many essential metals are needed to activate enzymes — molecules with important jobs in the body. And metals have many other essential roles as well. For example:

  • Calcium builds bones and teeth; activates enzymes throughout the body; helps regulate blood pressure; and helps muscles to contract, nerves to send messages, and blood to clot.

  • Chromium helps maintain normal blood sugar levels and helps cells draw energy from blood sugar.

  • Copper assists with metabolizing fuel, making red blood cells, regulating neurotransmitters, and mopping up free radicals.

  • Iron helps make hemoglobin (the oxygen-carrying chemical in the body's red blood cells) and myoglobin (a protein in muscle cells). Iron is essential for activating certain enzymes and for making amino acids, collagen, neurotransmitters, and hormones.

  • Magnesium, like calcium, builds bones and teeth. It also helps to regulate blood pressure and blood sugar and enables muscles to contract, nerves to send messages, blood to clot, and enzymes to work.

  • Manganese helps form bones and helps metabolize amino acids, cholesterol, and carbohydrates.

  • Molybdenum activates several enzymes that break down toxins and prevents the buildup of harmful sulfites in the body.

  • Potassium balances fluids in the body, helps to maintain a steady heartbeat and to make muscles contract, and may benefit bones and blood pressure.

  • Sodium balances fluids in the body, helps send nerve impulses, and helps make muscles contract.

  • Zinc helps blood clot, helps make proteins and DNA, bolsters the immune system, and helps with wound healing and cell division.

The pros and cons of root vegetables

They're packed with nutrients but high in starchy carbohydrates.


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Root vegetables — like turnips, rutabagas, and parsnips — may not be the sexiest foods on the table. But they're big celebrities in a number of cuisine trends like the "vegetable forward" movement (which elevates vegetables into creative entrees and side dishes) and root-to-stem cooking (which uses every part of a vegetable, including the tops, stems, and skins).

While it's fun to use old standbys in more interesting ways (like roasted parsnips with pistachio and lemon), it's important to eat root vegetables judiciously. "They are so high in carbohydrates that they are more like grains than greens. It makes more sense to put them in the same category as breads, rice, or pasta," says dietitian Teresa Fung, adjunct professor in the nutrition department at the Harvard T.H. Chan School of Public Health.

Six simple ways to smarter, healthier eating


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To eat a healthier diet, you need to combine nutritional science, a jolt of common sense, and pure enjoyment. Most of us know that fresh salad, berries, and slowing down when eating are better for us than wolfing down energy bars and sweets. But how to make that leap from our current habits to healthier ones?

Here are six ways you can eat healthy, delicious meals, and really enjoy what you're eating.

Do you need a daily supplement?

Most older adults take some kind of over-the-counter dietary supplement. But are these products right for everyone?


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Over-the-counter dietary supplements are big business — more than 90,000 products generate about $30 billion every year in the United States. Older adults make up a big part of these sales, too. A survey of almost 3,500 adults ages 60 and older published Oct. 1, 2017, in The Journal of Nutrition found that 70% use a daily supplement (either a multivitamin or individual vitamin or mineral), 54% take one or two supplements, and 29% take four or more.

But are these pills good medicine, or a waste of money?

Is low-fat or full-fat the better choice for dairy products?

The debate in the dairy case may come down to limiting overall fat intake.


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In the 1980s, fat came under fire, and low-fat or fat-free products became a dietary staple. But today, nutrition experts largely agree that dietary fat should have a spot at the table.

Healthy fats, including those found in olive oil, nuts, seeds, and avocados, can help your body absorb crucial nutrients and contribute to overall health. But does the same advice apply when it comes to dairy products? Is it time to trade in your low-fat and skim milk for whole milk and cheese? "Is whole milk better than low-fat milk? The answer is no," says Dr. Frank Hu, The Fredrick J. Stare Professor of Nutrition and Epidemiology at the Harvard T.H. Chan School of Public Health. "The evidence doesn't really support that."

Can taking aspirin regularly help prevent breast cancer?

Experts say there's little evidence that low-dose aspirin therapy brings benefits, and there are some risks.

In recent years, there's been a lot of talk about the potential benefits, and risks, of a regular regimen of low-dose aspirin. While much of the discussion has centered on whether taking low-dose aspirin can head off cardiovascular disease, some of the focus has also been on breast cancer. Can regular doses of this over-the-counter pain reliever reduce your risk of this common cancer?

For a while there were hints that the evidence was leaning that way. Back in 2017, this area of research, while still inconclusive, was somewhat promising. For example, a 2017 study published in Breast Cancer Research found that among some 57,000 women, those who reported taking low-dose aspirin (81 mg) at least three times a week had a 16% lower risk of breast cancer over all and a 20% lower risk of a specific type of hormonally driven breast cancer.

Can you supercharge the Mediterranean diet?

News briefs

A Mediterranean-style diet is rich in vegetables, legumes, fruits, whole grains, nuts, seeds, poultry, fish, and olive oil, and it's associated with lower risks for heart disease and diabetes. And a "greener" version of the eating style might be even more effective, according to a small, randomized study published online Nov. 23, 2020, by the journal Heart. Researchers — some from Harvard — recruited about 300 sedentary, middle-aged people (mostly men) with high cholesterol or abdominal obesity and divided them into three groups. One received guidance for exercise and a healthy diet; another received exercise guidance and was assigned to eat a calorie-restricted Mediterranean diet; and one group received exercise guidance and was assigned to eat a "greener" calorie-restricted Mediterranean diet with less animal-based and more plant-based proteins (including walnuts and a type of duckweed — an aquatic plant), plus lots of green tea. After six months, people on the "green" diet had lost more weight and inches around their middles, and had bigger drops in cholesterol, than people in the other two groups. "Green" dieters also had steeper declines in insulin resistance, inflammation markers, and diastolic blood pressure (the lower number in the measurement), compared with the other two groups.

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How do you avoid kidney stone attacks?

On call

Q. I want to avoid another kidney stone attack. What's your advice about diet, coffee, tea, and alcohol?

A. The foods you eat and the amount of fluid you drink can contribute to some types of kidney stones. Certainly, you can help prevent recurrent kidney stones by paying attention to your fluid and food intake.

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